O-255 UNRAVELLING THE IMMUNOGENETICS OF PREGNANCY: PARENTAL HLA-C ALLOTYPES ARE PREDICTIVE OF PREGNANCY LOSS AFTER SINGLE EUPLOID EMBRYO TRANSFERS Marin D Tao X Sun L Scott RTPresented at the 35th annual meeting of the European Society of Human Reproduction and Embryology.

O-208 VITAMIN D LONG-TERM TREATMENT DECREASES HUMAN UTERINE LEIOMYOMA SIZE THROUGH SPECIFIC MOLECULAR MECHANISMS IN A XENOGRAFT ANIMAL MODEL Corachán A Ferrero H Escrig J Monleón J Faus A Cervelló I Pellicer APresented at the 35th annual meeting of the European Society of Human Reproduction and Embryology.

O-048 Mitochondrial Stress Response Gene Clpp is Not Required for Granulosa Cell Function Esencan E Imamoglu GA Cozzolino M Seli EPresented at the 67th Annual Meeting of the Society for Reproductive Investigation.

Esencan E Simsek B Seli EPresented at the 67th Annual Meeting of the Society for Reproductive Investigation

T-217 Analysis of female demographics in the United States: relationship between education, fertility, and infertility service utilization.

S-214 Determination of Optimal Housekeeping Genes for Transcriptional Study of the Endometrium Maria Sanchez-Reyes J Spath K Sebastian-Leon P Wells D Diaz-Gimeno PPresented at the 67th Annual Meeting of the Society for Reproductive Investigation.

Gonzalez-Martin R Palomar A Pérez-Debén S Quiñonero A Dominguez FPresented at the 67th Annual Meeting of the Society for Reproductive Investigation

F-209 Mercury Disturbs Reproductive Functions of Primary Endometrial Stromal Cells (ESC).

Buigues A Marchante M Martínez J Pellicer A Herraiz SPresented at the 67th Annual Meeting of the Society for Reproductive Investigation

0-143 G-CSF Mobilized Plasma Regenerate Ovarian Stroma and Restore Ovarian Function.

Woodruff TK, Ataman-Millhouse L, Acharya KS, Almeida-Santos T, Anazodo A, Anderson RA, Appiah L, Bader J, Becktell K, Brannigan RE, Breech L, Bourlon MT, Bumbuliene Ž, Burns K, Campo-Engelstein L, Campos JR, Centola GM, Chehin MB, Chen D, De Vos M, Duncan FE, El-Damen A, Fair D, Famuyiwa Y, Fechner PY, Fontoura P, Frias O, Gerkowicz SA, Ginsberg J, Gracia CR, Goldman K, Gomez-Lobo V, Hazelrigg B, Hsieh MH, Hoyos LR, Hoyos-Martinez A, Jach R, Jassem J, Javed M, Jayasinghe Y, Jeelani R, Jeruss JS, Kaul-Mahajan N, Keim-Malpass J, Ketterl TG, Khrouf M, Kimelman D, Kusuhara A, Kutteh WH, Laronda MM, Lee JR, Lehmann V, Letourneau JM, McGinnis LK, McMahon E, Meacham LR, Mijangos MFV, Moravek M, Nahata L, Ogweno GM, Orwig KE, Pavone ME, Peccatori FA, Pesce RI, Pulaski H, Quinn G, Quintana R, Quintana T, de Carvalho BR, Ramsey-Goldman R, Reinecke J, Reis FM, Rios J, Rhoton-Vlasak AS, Rodriguez-Wallberg KA, Roeca C, Rotz SJ, Rowell E, Salama M, Saraf AJ, Scarella A, Schafer-Kalkhoff T, Schmidt D, Senapati S, Shah D, Shikanov A, Shnorhavorian M, Skiles JL, Smith JF, Smith K, Sobral F, Stimpert K, Su HI, Sugimoto K, Suzuki N, Thakur M, Victorson D, Viale L, Vitek W, Wallace WH, Wartella EA, Westphal LM, Whiteside S, Wilcox LH, Wyns C, Xiao S, Xu J, Zelinski M The explanation of basic scientific mechanisms responsible for oocyte and embryo competence is crucial for the future development of novel diagnostics and therapeutics in assisted reproduction (ART).Ī View from the past into our collective future: the oncofertility consortium vision statement. Abnormalities in ooplasmic level and/or the distribution of metabolic stores, structural proteins, mitochondria, RNAs may lead to aneuploidy or genetic abnormalities or to other cellular conditions that eventuate in a poor prognosis for the embryo viability and quality. The mechanisms of cytoplasmic anomalies underlying poor oocyte and embryo health are not well elucidated and present important new areas of research in IVF. Secondly, it suggests that the embryo problem originates from the oocyte. Clinical data suggests the decline in embryo implantation rate with increased maternal age is an “embryo problem” and not a uterine problem since use of donated oocytes results in high implantation and pregnancy rates in the same patient population.

IVF success rates clearly demonstrate a dramatic decline as maternal age approaches and pass the middle 30s.

Ivi meaning